Will having this ship (or any Drake ship for that matter) inherit any negative faction points by default due to the manufacturer reputation?
Cloud Imperium
No, overall, Drake is still seen as a reputable manufacturer, regardless of what purposes their clients decided to put their ships into. They won't be subjected to a back-end systemic bias or penalty just for owning one.
starfarer.space · Q&A: Drake Buccaneer - Part I